FREQUENCIES OF PREDICTED MIA ANTIGEN AMONG SOUTHERN THAI BLOOD DONORS

Background: The Mia antigen (MNS7) of the MNS blood group system is clinically important in Asian populations. Anti-Mia has been implicated hemolytic transfusion reactions and disease fetus newborn Thai However, data this frequency among southern Thais remains unknown.
 Objective: This study aimed to determine predict frequencies donors estimate risk alloimmunization Thais.
 Methods: A cross-sectional was conducted. Altogether, 400 500 central samples were genotyped for GYP(B-A-B) GYP(A-B-A) hybrids using polymerase chain reaction with sequence-specific primer (PCR-SSP).
 Results: Among them, 19 (4.45%), 28 (9.33%) positive set GP. Hut, GP.HF, GP.Mur, GP.Hop, GP.Bun. No GP.Vw phenotype found Thais. predicted Mi(a+)frequency significantly lower than northern (p<0.05). Its similar Vietnamese, Taiwanese, Southern Han Chinese populations (p>0.05) but differed from Indonesian, Filipino, (Guangzhou) both groups (p<0.05).
 Conclusion: constitutes first report Mi(a+) Thais, supporting estimation providing safety